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Member Spotlight: Eric Kmiec

New and More Precise CRISPR/Cas9 Technique Described

Eric Kmiec

Researchers at the Christiana Care Health System's Gene Editing Institute say they have developed a new system that allows them to not only repair damaged DNA within human cells, but also to determine when the DNA repair machinery has introduced unwanted genetic changes alongside, or instead of, the desired repair.

A team led by Eric Kmiec, Ph.D., director of the Gene Editing Institute at the Helen F. Graham Cancer & Research Institute at Christiana Care, published its findings using a modified version of the CRISPR/Cas9 gene-editing technique in PLOS ONE. The modified technique, called Excision and Corrective Therapy, or EXACT, uses an oligonucleotide to serve as both a bandage and a template during the repair of a genetic mutation. >>> Read full article

Kmiec, E. (2017). New and More Precise CRISPR/Cas9 Technique Described. Genetic Engineering and Biotechnology News. Retrieved from kmiec

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